Microreader CYP2D6*10, CYP2C9*3, ADRB1(1165G>C), AGTR1(1166A>C), ACE(I/D) and MTHFR(677C>T) gene
- 5 commonly used anti-hypertensive drugs and folic acid medication guidance
- Prompt the risk of hyperhomocysteinemia
Product Details
According to the „China Cardiovascular Disease Report (2016)”, the number of patients with hypertension in my country is 270 million, and hypertension has become the number one killer of Chinese residents’ health. Commonly used antihypertensive drugs include diuretics, β-receptor blockers, calcium channel blockers, angiotensin converting enzyme inhibitors, and angiotensin II receptor blockers.
In clinical practice, it is common for different individuals to receive the same anti-hypertensive drug treatment, and there are obvious differences in the efficacy and adverse reactions. Studies have shown that genetic factors are important reasons for this difference. The distribution and mutation frequency of genes in the population are different, and the response to antihypertensive drugs is also different.
Detection significance
Commonly used hypertension drugs classification and name
Product features
▶No extraction
No need to extract DNA, save time and effort, reduce pollution.
▶Simple and fast operation
Combined testing of conventional hypertension drugs and folic acid related drugs, 1 tube amplification, the whole process only needs 3h.
▶Anti-pollution system
UNG anti-pollution system, effectively avoiding PCR product contamination.
▶Rich project experience
Professional software assists in result analysis and interpretation, which is fast and easy. Suitable for automated and batch testing.
Applicable people
Hypertensive patients, patients with family history of hypertension, and people who have requirements for their own health management.
References
1.Songtao Ben,et al.,Hum Genomics. 2016; 10: 11.
2 Evol Med Public Health. 2013; 2013(1): 118‒134.
3. Jasmine A. et al.,Pharm Res. 2017 Aug; 34(8): 1615‒1625.
4 Ch ai -Min Chung et al.,PLoS One. 2013; 8(3): e56119.
5. Rational drug use for hypertension (2nd edition).