scATAC + RNA-seq
Matched chromatin accessibility and gene expression from the same nucleus for integrated multi-omic insights.
Introduction
Highlights
Matched Modalities per Nucleus
ATAC and RNA captured from the same cell
Regulatory–Expression Integration
Supports mechanistic interpretation of gene regulation
Random-Primed RNA Strategy
Enables full-length coverage and non-polyA RNA detection
Dual-Index Library Design
Minimizes index hopping and supports flexible sequencing modes
Workflow
From Sample to Insight in Seven Steps
Prepare Nuclei
Fresh,frozen,or fixed samples
Tn5 Tagmentation
Tag accessible chromatin
Microfluidic Partitioning
Barcode ATAC and RNA from the same cell
Pre-amplification
Pre-amplification of cDNA & ATAC fragments
Library Prep
Construct ATAC and expression libraries separately
Sequencing
Generate paired datasets
Bioinformatic Analysis
View gene expression and chromatin accessibility together
Product Features
- Human
- Rodents
- Primates
- Amphibians
- Blood
- Cultured cells
- Sorted cells
- Cell suspension
- Nuclei suspension
- Fresh tissue
- Frozen tissue
- Organoid
Components
|
Product Name |
Product Code |
Specification |
|---|---|---|
|
SeekOne™ DD Single Cell Multiome ATAC + RNA Kit |
K02901-08 |
8 tests |
|
Components Name |
Components Code |
Specification |
|---|---|---|
|
SeekOne™ DD Chip S3 Kit |
K00202-0801 |
8 tests |
|
SeekOne™ DD scFAST-seq Barcoded Beads Kit |
K00801-0802 |
8 tests |
|
SeekOne™ DD Single Cell DNA Tagmentation Kit |
K02901-0801 |
8 tests |
|
SeekOne™ DD Single Cell Multiome Droplet Reaction Kit (ATAC + RNA) |
K02901-0802 |
8 tests |
|
SeekOne™ DD Single Cell Multiome Amplification Kit (ATAC + RNA) |
K02901-0803 |
8 tests |
|
SeekOne™ DD Library Construction Kit |
K00202-0804 |
8 tests |
|
SeekOne™ DD Single Cell Cleanup Kit |
K00202-0805 |
8 tests |
Compatible Instrument
SeekOne™ Digital Droplet System
A high-throughput, automated single-cell multi-omics platform based on microfluidic water-in-oil technology for single cell/nucleus separation and barcoding.
Compatible Software
SeekArc™ Tools
SeekSoul™ Online
Data Analysis
SeekArc™ Tools
SeekSoul™ Online
