scMethyl + RNA-seq
Simultaneous single-cell methylation and RNA profiling at single-base resolution for integrated epigenetic and transcriptional insights.
Introduction
Highlights
Complete Multiomics
Integrated analysis of DNA methylation, transcriptome, V(D)J, and CNV.
High-throughput
Capture tens of thousands of cells per run, enabling large-scale studies.
Single-Cell Resolution
High-resolution profiling reveals true cellular heterogeneity beyond bulk averaging.
Broad Sample Compatibility
Compatible with nuclei or whole cells, fresh or frozen tissues, and blood.
Workflow
From Sample to Insight in Six Steps
Sample Prep
Tissue dissociation & cell suspension QC
Tn5 Tagmentation
Microfluidic Partitioning
Barcode Methyl and RNA from the same cell
Library Prep
Construct expression libraries and methylation libraries
Sequencing
Generate paired datasets
Bioinformatic Analysis
Analyze gene expression and methylation together
Product Features
- Human
- Mouse
- Blood
- Cultured cells
- Sorted cells
- Cell suspension
- Nuclei suspension
- Fresh tissue
- Frozen tissue
- Organoid
Components
|
Product Name |
Product Code |
Specification |
|---|---|---|
|
SeekOne™ DD Single-Cell Multiome Methylation+RNA Kit |
K00901-08 |
8 tests |
|
Components Name |
Components Code |
Specification |
|---|---|---|
|
SeekOne™ DD Chip S3 Kit |
K00202-0801 |
8 tests |
|
SeekOne™ DD Cell Fixation and Nucleosome Depletion Kit |
K00901-0801 |
8 tests |
|
SeekOne™ DD Single Cell Multiome Purification Kit (Methyl+RNA) |
K00901-0804 |
8 tests |
| SeekOne™ DD Single Cell Multiome Droplet Reaction Kit (Methyl+RNA) |
K00901-0803 |
8 tests |
|
SeekOne™ DD Single Cell 5' cDNA Amplification Kit |
K00501-0806 |
8 tests |
| SeekOne™ DD Single Cell Nextera Library Prep Kit |
K00901-0806 |
8 tests |
|
SeekOne™ DD Single Cell DNA Methyl Library Prep Kit |
K00901-0805 |
8 tests |
| SeekOne™ DD Single Cell Methyl Barcoded Beads Kit |
K00901-0802 |
8 tests |
Compatible Instrument
SeekOne™ Digital Droplet System
A high-throughput, automated single-cell multi-omics platform based on microfluidic water-in-oil technology for single cell/nucleus separation and barcoding.
Compatible Software
SeekSoul™ Methyl Tools
SeekSoul™ Online
Data Analysis
SeekSoul™ Methyl Tools
SeekSoul™ Online
